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... The mainstay treatments for spondyloarthritis are disease-modifying antirheumatic drugs (DMARDs), such as methotrexate and biologic tumor necrosis factor (TNF) inhibitors adalimumab (Humira), infliximab-dyyb (Inflectra), and golimumab (Simponi).Starting treatment early can delay or even prevent irreversible spine curvature, limited mobility, and disability ...