I have pain in my shoulders back of head neck and uppercut back which is aggravated by lying down because of pressure o. These parts of my body so,very difficult to sleep
October 11
That sounds like a really challenging situation — managing spondylitis when NSAIDs are off the table due to colitis, and having already tried multiple biologics including Rinvoq, really narrows the path. You're not alone in facing this.
Since NSAIDs and three biologics haven't worked, there are still some other options worth Show Full Answer
That sounds like a really challenging situation — managing spondylitis when NSAIDs are off the table due to colitis, and having already tried multiple biologics including Rinvoq, really narrows the path. You're not alone in facing this.
Since NSAIDs and three biologics haven't worked, there are still some other options worth discussing with your rheumatologist: Other biologic classes that may still be options:
- IL-17 inhibitors like Cosentyx (secukinumab) or Taltz (ixekizumab), if not yet tried
- TNF inhibitors like Humira, Cimzia, Enbrel, Simponi, or Remicade — some of these also help with colitis, which could be a dual benefit worth exploring with your doctor
Non-medication approaches to discuss:
- Physical therapy and targeted exercise to manage stiffness and pain
- Corticosteroid injections for specific joints (short-term relief)
- Multidisciplinary pain management programs It's really important to advocate strongly for yourself with your rheumatologist, especially given how complex your situation is. A second opinion from another rheumatologist who specializes in spondylitis may also open new doors.
October 11
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