Has Anyone Experienced A Wearing Off Effect Following Success With Medications? | MySpondylitisTeam

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Has Anyone Experienced A Wearing Off Effect Following Success With Medications?
A MySpondylitisTeam Member asked a question 💭

I was diagnosed with 'non radiographic' AS (although it's questionable about the NR b/c my doctor saw inflammation on the MRI, brought it to the attention of the radiologist who then agreed) and started with taking Piroxicam at night. Initially and for the first time in my life I woke up in the morning without pain. I then was prescribed Cimzea (the medication for NR AS). It's been close to a year and recently, I started having the same pain in the morning where it's difficult to straighten up… read more

posted August 10, 2022
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A MySpondylitisTeam Member

I found pt to be extremely aggravating for my hips and sacroiliac joint. It is worth the try though.
I have found my body builds an immunity against the meds so they all stop working within a couple years. My rheumatologist rotates my meds to help prevent this and give me consistent care.

posted August 15, 2022
A MySpondylitisTeam Member

New to this AS. Started with Celebrex and am now on Naproxen. I would like to stay on OTC NSAIDS if possible. Also found that morning stretches on Spondylitis Association of America called Back in Action Again works wonders. Also doing stretches and movements before getting out of bed helps, too.

posted August 13, 2022
A MySpondylitisTeam Member

I have had AS for 21 years and still doing ok. I started with the typical NSAIDS then Vioxx which helped a lot until they took it off the market. Since then I have used about 6 different TNF blockers (Enbrel, rhemicade, Simponi and others). They would seem to last 2 to 3 years before it wasn’t helping anymore. I have used Cimzia for the last 7 years and has worked well. One of my Rheumatologist recommended taking Methotrexate with the TNF blocker. I would not take because it has too many side effects.

posted September 1, 2022
A MySpondylitisTeam Member

Hi there, an mri of your brain will show ms…….. it shows as lesions or white lines and patches on the brain

posted August 16, 2022
A MySpondylitisTeam Member

Anything is possible. I've been on medication that I questioned about whether it was wearing off. I quit taking the medication for one week, started back on it and it worked great.
Don't do this with your medication until you talk to your doctor about it, please.

posted March 19

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