Answer Summary

Members strongly affirmed that ankylosing spondylitis commonly causes leg weakness, muscle spasms, and cramping, with many sharing how these... Read more

Members strongly affirmed that ankylosing spondylitis commonly causes leg weakness, muscle spasms, and cramping, with many sharing how these symptoms have progressed to require mobility aids like canes, walkers, or wheelchairs, and describing frightening experiences of their legs suddenly giving out without warning. Several members found relief through medications like Gabapentin, Baclofen, and Lyrica for spasms, steroid injections for numbness and swelling, and muscle relaxers, though many emphasized that consistent morning and evening stretching, staying active throughout the day, and exercises like biking are essential to managing tightness caused by inflammation. A recurring theme was the importance of listening to your body, using supportive aids without shame, and maintaining movement and stretching routines to slow progression and preserve mobility for as long as possible.