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... ReferencesAnkylosing Spondylitis— Mayo Clinic The Heart in Spondylitis — Spondylitis Association of AmericaCardiac Involvement in Ankylosing Spondylitis — Journal of Clinical Medicine Research Cardiovascular Risk of Nonsteroidal Anti-Inflammatory Drugs: An Under-Recognized Public Health Issue — CureusTypes of Aortic Valve Disease — NYU Langone HealthCardiomyopathy ...

... In some people with spondylitis, inflammation can affect the aortic valve (the flap that controls blood flow from the heart into the aorta). Over time, this can cause the valve to thicken or lose flexibility, leading to a condition called aortic insufficiency. ...

... Cardiovascular issues may include: Aortitis — Inflammation of the aorta, the largest artery in the body, which can lead to aortic insufficiency (inability of the aorta to supply the body with enough blood) and high blood pressure Aortic valve disease — A disorder in which the valve between the heart’s largest pumping chamber (left ventricle) and the ...

... These complications may include: Coronary artery disease Abnormal heart rhythm Inflammation of the aorta, the large blood vessel that carries blood from the heart to other parts of the body Heart valve diseases Problems with the heart muscle that that impair its ability to pump blood effectively Read more about how AS affects the heart.Gastrointestinal ...