Great question! If TNF blockers aren't working well or aren't the right fit, there are other treatment options available for spondylitis. Here's a quick overview:
Interleukin (IL) Inhibitors
These are biologic drugs that work differently from TNF blockers — they target molecules called interleukins that trigger Show Full Answer
Great question! If TNF blockers aren't working well or aren't the right fit, there are other treatment options available for spondylitis. Here's a quick overview:
Interleukin (IL) Inhibitors
These are biologic drugs that work differently from TNF blockers — they target molecules called interleukins that trigger inflammation. Options include:
- Secukinumab (Cosentyx)
- Ixekizumab (Taltz)
- Ustekinumab (Stelara)
They are given by injection under the skin and can be very effective. However, they do carry a risk of increased infections and may affect inflammatory bowel disease, so it's worth discussing this with a doctor.
JAK Inhibitors
These are oral tablets taken daily, making them a convenient alternative to injections. Options include:
- Tofacitinib (Xeljanz)
- Upadacitinib (Rinvoq)
These work by blocking specific pathways in the immune system that drive inflammation. Each option comes with its own set of potential risks and benefits, so it's really important to have an open conversation with a rheumatologist to figure out which one suits individual needs best. No two spondylitis journeys are exactly the same!
September 22
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