There are many individuals on this site who are struggling with symptoms while testing positive for HLA-B27 and diagnosed negative for AxSpa. What you may not know is that this gene is linked to other conditions which can mimic AxSpa. One such condition is EDS. If you have a life history of hypermobility then it may help to ask your healthcare team about this condition:

What Research Shows for Prevalence in EDS: Studies on hypermobile Ehlers-Danlos syndrome (hEDS) show that roughly 24% of… read more

About ankylosing spondylitis and Ehlers-Danlos syndrome

https://www.medicalnewstoday.com/articles/ankylosing-spondylitis-and-ehlers-danlos-syndrome

Fifty years after the discovery of the association of HLA B27 with ankylosing spondylitis

https://pmc.ncbi.nlm.nih.gov/articles/PMC10476136/

Ehlers-Danlos syndrome hypermobility type is associated with rheumatic diseases

https://pmc.ncbi.nlm.nih.gov/articles/PMC5209734/

HLA-B27 Test: Purpose and Results | Testing.com

https://www.testing.com/tests/hla-b27/

HLA-B27 - Wikipedia

https://en.wikipedia.org/wiki/HLA-B27