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A MySpondylitisTeam Member asked a question 💭
Aliquippa, PA
July 25
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MySpondylitisTeam

That's a really important question, especially for veterans. Unfortunately, there isn't enough information available to provide a reliable answer on a confirmed link between Agent Orange exposure and ankylosing spondylitis (AS).

What is known is that AS is strongly influenced by genetics, particularly the HLA-B27 gene Show Full Answer

That's a really important question, especially for veterans. Unfortunately, there isn't enough information available to provide a reliable answer on a confirmed link between Agent Orange exposure and ankylosing spondylitis (AS).

What is known is that AS is strongly influenced by genetics, particularly the HLA-B27 gene, which accounts for about 30% of the inherited risk. Environmental triggers may also play a role in activating the condition in those who are genetically predisposed.

If there's a concern about this, the best steps would be to:

- Speak with a rheumatologist about your full health history, including any chemical exposures
- Contact the VA (Department of Veterans Affairs) if you're a veteran, as they track health conditions linked to Agent Orange
- Ask about genetic testing for HLA-B27 if not already done

A rheumatologist can help piece together the full picture and guide the best path forward for managing AS symptoms.

July 25

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