MySpondylitisTeam

Can ankylosing spondylitis cause neuropathy in the legs?

Yes, neuropathy in the legs can be associated with AS. Research shows that neuropathic pain is common in people with AS, with studies finding that about one-third to a majority of individuals with AS experience this type of pain.

MySpondylitisTeam members describe Show Full Answer

Can ankylosing spondylitis cause neuropathy in the legs?

Yes, neuropathy in the legs can be associated with AS. Research shows that neuropathic pain is common in people with AS, with studies finding that about one-third to a majority of individuals with AS experience this type of pain.

MySpondylitisTeam members describe various symptoms including:
- Numbness and tingling ("pins and needles")
- Weakness in the legs
- Complete loss of feeling from the waist down
- Pain and throbbing sensations
- Difficulty with mobility and daily activities like walking or driving

How does AS cause leg neuropathy?

AS can lead to nerve damage through several mechanisms:
- Spinal fusion and extra bone growth (bamboo spine) can compress nerves
- Inflammation and swelling in the spine reduce space for nerves to move
- Changes in posture from spinal stiffness can affect nerve function
- Vertebral fractures from reduced spine flexibility may compress nerve roots

In rare cases, AS can cause cauda equina syndrome, where pressure on nerve roots at the end of the spinal cord causes weakness, tingling, or numbness in the legs and feet. This is a serious complication requiring immediate treatment.

Neuropathy is associated with lower quality of life and worse disease activity in AS, so it's important to discuss these symptoms with your doctor for proper evaluation and treatment.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Can Spondylitis Cause Neuropathy?