Biologics suppress only one or a small class of inflammatory cytokines. When this happens, sometimes other types of cytokines are activated to go on the mission of attack because the body just knows something is in it that should not be there. It's like a family defending their home. If one member is down, another takes their place. When this happens new symptoms emerge and are given a new name. But the name is not what is important. It's the reaction that is the body still seeking to attack the invading substance that is important. The body is doing all it can to get the brain to pay attention and hopefully seek out the invading organism. Deep dive testing is the only way to reveal the source of the danger signals causing inflammation. That will continue regardless of medications until the source is eradicated. Seek out testing from a lab that goes deeper and if you cant find a lab, seek out a functional medicine practitioner who orders the tests. Be prepared though, some of the tests are very pricey and the insurance company might not cover the cost. I started with ordering my own tests through Life Extension. I ordered them online, they sent me instructions what to do at home and send the samples back to the lab. Then they sent me a report of the results as well as what i could do to treat the conditions found. I then hired a functional medicine dr to help me navigate a few more tests as well as nutritionally treat my discovered conditions. A good functional medicine practice will also have a stress management counselor and a dietician on staff. Psoriasis is frequently related to streptococcus hiding in the body and is commonly activated by high stress. Spondylitis is commonly involved with klebsiella pneumoniae. Borellia (Lyme), parasites, mold mycitoxins, and heavy metals are commonly involved too. Let me know if you need more details on how to go this route of clearing your body to get it to settle down. Yours in better health P 😌🙏

Hey there beautiful peeps. I knew a pal on mypsoriasteam who had this condition. Hers was caused by stress and smoking. She told me there is a forum like this one for that condition. You might find more help with it there. At the end of the day though, it's really all about testing deeply to reveal the causes, then address those to get a handle on the disease, same as for all the autoimmune b.s. we deal with. Very few, if any, meds actually help get rid of it. Something that occurred to me not long ago is that the most people i see on this and other sites who seem to be the worst affected live in humid climates prone to mold development in the home. When i uncovered an enormous mold source in my home and got rid of it, my conditions made a big noticeable improvement. A deep dive mold test through my functional medicine dr revealed about a dozen species in my blood. It's a source worth looking into, especially if you have brain affects along with all the other crapola. 🫤🙏

I have the exact same problem

Hi Rob no I think a lot of people haven’t I am not sure if it’s from having the AS or another effect from the biolgic I was on but it started after the biolgic my skin was normal before that, the HS and the other spots/ boiis etc are still there now and come up anytime I never know just happens.
I didn’t know you could take morphine for the pain and glad you have no issues with it, I can’t take Dizapam the doc isn’t in agreement with taking it regularly and only gives me six at a time the last time was a year ago, I live in the uk so maybe that’s why.
I am so sorry what has happened with the psoriasis, so you take diazepam and morphine and nothing else?
You’re very welcome I just hope things improve for you. Hugs 🤗

I have never heard of this before, and I've been on morphine for a bit over 10 years with no issues. BUT, Enbril, after a year gave me the nastiest case of psoriasis from head to toe and it's taken me years to almost get it manageable. My finger/toe nails are awful and ingrown, with ridges and they lift up from the nail beds at times. That and the body sores, scaley skin and chunks of skin on my head. Thank you for more information to research and good luck.