How does ankylosing spondylitis affect the body beyond pain?
Ankylosing spondylitis impacts the body in several ways beyond causing pain. The chronic inflammation can lead to complications affecting multiple organs and body systems.
Structural Changes
- New bone formation in the spine that may cause spinal fusion Show Full Answer
How does ankylosing spondylitis affect the body beyond pain?
Ankylosing spondylitis impacts the body in several ways beyond causing pain. The chronic inflammation can lead to complications affecting multiple organs and body systems.
Structural Changes:
- New bone formation in the spine that may cause spinal fusion (ankylosis)
- "Bamboo spine" appearance on X-rays in some cases
- Kyphosis (rounding of the spine)
- Increased risk of spinal fractures due to stiffer, weaker bones
Joint and Musculoskeletal Effects:
- Stiffness, especially in the morning, lasting one to two hours
- Reduced flexibility and mobility
- Posture problems
- Potential need for mobility devices in severe cases
Fatigue:
Chronic fatigue is common because the body works harder to fight ongoing inflammation, leaving you feeling drained of energy. A MySpondylitisTeam member shared they can push through pain, but functioning feels impossible when completely depleted.
Eye Problems:
Vision issues can develop as complications of the inflammatory process.
Heart Complications:
Between 2-10% of people experience cardiovascular issues, including:
- Aortitis (inflammation of the aorta)
- Aortic valve disease
- Heart rhythm abnormalities
- Cardiomyopathy (weakened, enlarged heart)
- Reduced blood flow to heart muscle Digestive System:
Some people experience digestive complications like diarrhea and stomach pain.
Nervous System:
Rarely, cauda equina syndrome can develop, where inflammation causes scarring in nerves at the base of the spinal cord.
Breathing Difficulties:
Rib cage stiffness and chest fusion can make it harder for the chest to expand properly during breathing.
Quality of Life Impact:
- Brain fog affecting daily functioning
- Difficulty maintaining employment or active lifestyle
- Poor appetite and unexpected weight loss
- Challenges with routine tasks
The good news is that with proper treatment, many people can achieve periods of remission where symptoms are minimal or absent.
November 4, 2025
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