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Real members of MySpondylitisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Was never allergic to anything before. NSAIDS increase pain. Ive tried natural NSAIDS, too. Same reaction. Steroidals have started causing itching in my ears.

May 25, 2025
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A MySpondylitisTeam Member

I can't say whether a symptom of A.S. I have Iga deficiency and it causes me to have reactions to almost everything..soaps,lotions, medication etc..so as of now no biological therapy..

June 8, 2025
MySpondylitisTeam

While NSAID sensitivity isn't a direct symptom of AS, it can be a challenging complication that affects treatment options. When NSAIDs cause increased pain or adverse reactions, it's important to work closely with your healthcare provider to explore alternative treatment approaches.

If you're experiencing new sensitivities Show Full Answer

While NSAID sensitivity isn't a direct symptom of AS, it can be a challenging complication that affects treatment options. When NSAIDs cause increased pain or adverse reactions, it's important to work closely with your healthcare provider to explore alternative treatment approaches.

If you're experiencing new sensitivities to both NSAIDs and steroids, this should be documented and discussed with your rheumatologist immediately. These reactions could impact your treatment plan and require adjustments. Alternative treatment options may include:
- Biologic medications, particularly TNF inhibitors
- Disease-modifying antirheumatic drugs (DMARDs)
- Carefully monitored different types of steroids (if only some cause reactions)
- Lifestyle modifications including regular exercise and stress management

Always report any new medication reactions to your healthcare provider immediately, as they may need to adjust your treatment plan or explore different medication combinations that work better for your specific situation.

May 25, 2025

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