My doc tried to get me in a drug trial but the mri didn’t show inflammation and hla b27 was negative so I don’t qualify. Now I’m stressed that this info will make him rethink my diagnosis. I was happy(sort of) to finally having an answer to why I’m in so much pain all the time and get on track to feeling better(sort of). His diagnosis was based on deteriorating of the si joints caught on an X-ray.
Yes, it is possible to be HLA B27 negative and still have spondylitis. 85% of people with axial spondylitis are HLA B27 positive, but that still leaves 15% of people who aren't.
I tested Negative and still got dx from rheumatologist. My rheumatologist said I have fibromyalgia with underlying spondylosis or ankylosing spondylitis. A negative blood test does not mean much really. The doctor needs to look at all things together meaning your pain areas your pain levels how long have you been in pain. Etc. Hope you find answers. It took me over three years to get my diagnosis thankfully now I am starting methotrexate. Not much has changed as far as my pain level. I’ve been on methotrexate six weeks And this is my second medication already on top of everything else that I take.
I'm in limbo. Still trying to get a diagnosis. I just keep getting referred to pain management for injections that don't help.