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Ive been in Remicade since Jan.2024 ana just released from a 5 day hospital stay for SEVERE Cellulitis in my right infusion arm. Yuppers! My meds caused the infection that had me meet the Infectious Disease MD team. After reading the horrific stories of others like me from getting that med IV style, i can't believe it's still offered! When i was released I saw my Rheumatoid Dr & first words out of her mouth, " Your done, NO MORE infusions. Your now going to get injectables". She knew exactly… read more

November 12, 2025
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A MySpondylitisTeam Member

They all weaken your immune system and make you susceptible to severe infections from any source. It is unfortunate that the advertised disclaimers about this very real and common risk are not emphasized more in advertising, inserts, and doctors who prescribe them. So sorry to read of your horrific experiences. Are you going to continue with biologics? Injections, pills, all of it are just as risky. Crazy Medical team stumping infections abound. Here's a Pic of one that got in my hand Heaven knows how while weaning off at short course of prednisone last Spring. I think we should all count our blessings sometimes that we have overactive immune systems and just leave our bodies alone. At the very least, maybe we should try to just treat ourselves more gently to combat excess inflammation. Slow down, eat better, get some rest....

December 2, 2025
A MySpondylitisTeam Member

I was taking it for over a year. Now im on cosentyx injections because rinvoq wasnt "doing enough"

December 2, 2025
MySpondylitisTeam

Are others taking Rinvoq for AS?

I'm so sorry to hear about your hospital stay - that sounds really scary! Yes, Rinvoq (upadacitinib) is approved for treating AS and is being used by people with ankylosing spondylitis.

Rinvoq is a JAK inhibitor that's taken orally as a tablet every day, which means no more infusions or Show Full Answer

Are others taking Rinvoq for AS?

I'm so sorry to hear about your hospital stay - that sounds really scary! Yes, Rinvoq (upadacitinib) is approved for treating AS and is being used by people with ankylosing spondylitis.

Rinvoq is a JAK inhibitor that's taken orally as a tablet every day, which means no more infusions or injections. This makes it a good option when switching from infusion treatments like Remicade.

In clinical studies, about 52 percent of people with AS taking Rinvoq showed improvements in pain and inflammation. It works differently than TNF inhibitors like Remicade - it targets the JAK1 protein to reduce inflammation.

Some important things to know about Rinvoq:

* It can increase risk of infections (like other AS biologics)
* May increase risk for certain cancers
* Can be a risk factor for blood clots
* Common mild side effects include nausea, headaches, diarrhea, or high cholesterol
* Rarely, it could affect liver or kidney function

Your friend's positive experience with rheumatoid arthritis is encouraging! Many people find that switching to an oral medication improves their quality of life compared to infusions.

Make sure to discuss all potential risks and benefits with your rheumatologist, especially given your recent infection and your spinal stenosis and scoliosis.

November 12, 2025

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