Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MySpondylitisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MySpondylitisTeam Member asked a question 💭
Munich, DE
July 7, 2025
 · 
Be the first to react
MySpondylitisTeam

There are currently two FDA-approved JAK inhibitors for treating spondylitis:

• Tofacitinib (Xeljanz) - Approved for ankylosing spondylitis
• Upadacitinib (Rinvoq) - Approved for both ankylosing spondylitis and non-radiographic axial spondyloarthritis A key advantage of JAK inhibitors is that they are taken as oral pills Show Full Answer

There are currently two FDA-approved JAK inhibitors for treating spondylitis:

• Tofacitinib (Xeljanz) - Approved for ankylosing spondylitis
• Upadacitinib (Rinvoq) - Approved for both ankylosing spondylitis and non-radiographic axial spondyloarthritis A key advantage of JAK inhibitors is that they are taken as oral pills rather than injections, unlike biologic medications. However, they don't stay in the body as long, which means symptoms may return more quickly if treatment is stopped.

In clinical trials, these medications have shown promising results in reducing inflammation and pain for people with spondylitis who haven't responded well to other treatments.

July 7, 2025

Related Questions

View All
A MySpondylitisTeam Member asked a question 💭
Tiffin, OH

A MySpondylitisTeam Member asked a question 💭
Bellefonte, PA

A MySpondylitisTeam Member asked a question 💭
Northumberland uk