Yes, spondylitis is both an autoimmune and inflammatory condition. In this condition, your immune system mistakenly attacks healthy tissues in your body, particularly targeting the joints and spine. This inappropriate immune response leads to chronic inflammation.
The condition primarily affects the neck and spine, but can Show Full Answer
Yes, spondylitis is both an autoimmune and inflammatory condition. In this condition, your immune system mistakenly attacks healthy tissues in your body, particularly targeting the joints and spine. This inappropriate immune response leads to chronic inflammation.
The condition primarily affects the neck and spine, but can also impact:
- Hips
- Eyes
- Bowels
- Tendons
- Other joints Spondylitis is classified as an MHC-I-opathy, meaning it's caused by abnormal proteins that don't function properly rather than by autoantibodies. This dysfunction triggers an inappropriate immune response in your body.
Most cases develop before age 45, with many people experiencing their first symptoms in their 20s or 30s. It's relatively rare, affecting about 1% of the population.
June 24, 2025
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