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Real members of MySpondylitisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
June 19, 2025
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MySpondylitisTeam

Yes, this is a common experience with biologic medications. Sometimes biologics can become less effective over time because your body develops antibodies against the medication. This happens in about 20-30% of people taking biologics for spondylitis.

When a biologic stops working effectively, doctors typically recommend Show Full Answer

Yes, this is a common experience with biologic medications. Sometimes biologics can become less effective over time because your body develops antibodies against the medication. This happens in about 20-30% of people taking biologics for spondylitis.

When a biologic stops working effectively, doctors typically recommend switching to either:
- A different biologic of the same class
- A biologic from a different class
- Another type of medication entirely It's important to discuss these changes with your doctor, as they can:
- Review your current symptoms
- Evaluate if it's time to switch medications
- Suggest alternative treatment options
- Modify your dosage if needed

Remember that finding the right treatment can take time, and it's normal to need adjustments along the way.

June 19, 2025

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