I'm on cosentyx year 3 it helps but any joint damage already done is done. So no biologic will prevent existing pain, but can help mitigate future pain. I highly recommend cosentyx or trying another biologic if your rheumatoid ologist thinks it's more appropriate. I used to have ribcage pain couldn't take a full breath its gone now.

Hello Trent, yes - the SI joint gives me the most trouble out of everything. I have minimal back issues. May I ask if you're on any biologics? I've read that Humira doesn't do much to help with SI joint pain for most people. With SI joint pain being my biggest complaint...not sure if I want to make the leap to Humira.
Thank you for your response!

Thank you so much for sharing your story

The BIG difference is Celebrex treats the symptom (it is a NSAID). Humira (TNF Inhibitor) may slow progression as well as relieve pain via reducing inflammation.

I was on Humaira for about 12 years. Research I read says it's efficacy starts reduce after 5 years. In my case it was 1X monthly, than 2X ;leading to weekly. It did a decent job. But, as all biologicals, there are side effects. My were nerve damage (peripheral neuropathy) and a lot of skin cancer (mostly squamous and one melanoma requiring major surgery).

I too rejected injected myself with anything. But I was not getting a lot of relief with NSAIDs). So after much encouragement from my doctor I started it. I also tried Taltz (in the IL-17A inhibitor family) and had bad side effects that I did not relate to the drug until it got very bad.

I looked at JAK inhibitors too, but I felt the risks were too great for me (personally). I quit biologicals about 7 months ago and I am mostly OK. But I'm 71

Biologicals are a very tough decision that no one can make for you. They can help, but it is questionable for long term efficacy and you may have to deal with some unpleasant side effects.

Cosentyx and a surgery to fuse my si joint has improved my life exponentially. I think I will need get my left side fused as well. Don't be afraid to get some titanium pins. The amount of pain involved in the surgery. Is so much less than living a few months barley able to walk.