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Real members of MySpondylitisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
February 1, 2023
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MySpondylitisTeam

Switching from methotrexate (MTX) to Humira (adalimumab) is a common step for many with ankylosing spondylitis. Here are some key points from the knowledge base:

- Administration: Humira is administered every other week by subcutaneous injection, available as a pen or prefilled syringe
- Time to Effectiveness: Biologic Show Full Answer

Switching from methotrexate (MTX) to Humira (adalimumab) is a common step for many with ankylosing spondylitis. Here are some key points from the knowledge base:

- Administration: Humira is administered every other week by subcutaneous injection, available as a pen or prefilled syringe.
- Time to Effectiveness: Biologic drugs like Humira can take a few months to relieve symptoms. Some people may notice improvements sooner, but it often takes up to six months to see the full benefits.
- Side Effects: Common side effects include respiratory infections, headache, redness or irritation at injection sites, and rash. Rare but serious side effects include severe allergic reactions, potentially fatal infections, and an increased risk of certain cancers like lymphoma.

It's important to stay in close contact with your rheumatologist to monitor your progress and manage any side effects.

July 25, 2024

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