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I have as my son also suffers with bad back. Im hoping I havent passed it on?

March 16, 2018
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Answer Summary

Members overwhelmingly confirmed that spondylitis has a hereditary component, often involving the HLA-B27 gene, though they emphasized that... Read more

Members overwhelmingly confirmed that spondylitis has a hereditary component, often involving the HLA-B27 gene, though they emphasized that carrying the gene does not guarantee developing symptoms and that testing negative does not rule out the condition. Many members shared powerful family stories spanning multiple generations, with parents, siblings, children, and even grandparents affected, while noting that some carriers remain symptom-free and others develop issues that may not be formally diagnosed until symptoms worsen. A recurring theme was the importance of genetic testing when available, monitoring family members for joint or back pain, and consulting a rheumatologist early, coupled with reassurance that hereditary risk does not mean certainty for every descendant.

A MySpondylitisTeam Member

definitely genetic predisposition but that doesn't mean get symptoms

March 17, 2018
A MySpondylitisTeam Member

It is inherited but not all decendants will get it. Several genes involved.

April 9, 2018
A MySpondylitisTeam Member

I have ankylosing spondylitis. I was told that it was thought to be a gene issue. This means that it can be passed from one generation to another but could skip a few if the gene became dormant. I have no knowledge of anyone in my family with the condition currently and the older generations have passed so.... its always best to see a dr and get tests if availble.

March 20, 2018
A MySpondylitisTeam Member

You can be tested for the HLAB27 gene, but e en if the test is negative, you can still have it. There are other genes at work.

April 3, 2018
A MySpondylitisTeam Member

My rheumatologist told me they don't know for definite if it is hereditary but his opinion is that it is, my grandad had it, my dad has it, I have it and my other sister suffers with a bad back and was tested for the gene and has it too but she has never been diagnosed she said when it starts to get worse she will go see rheumatologist so I guess it is hereditary. 😥

May 6, 2018

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