Trexall is a prescription drug approved by the Food and Drug Administration (FDA) to treat severe cases of psoriasis, rheumatoid arthritis, and some types of cancer. Methotrexate is sometimes prescribed to treat spondylitis. Trexall is also referred to by its drug name, Methotrexate.

Trexall is an immunomodulator, or drug that modifies the immune system. Trexall is a type of disease-modifying antirheumatic drug (DMARD). Trexall is believed to suppress the immune system in several ways, reducing the activity of T cells, B cells, interleukins, and enzymes that play a role in autoimmune attacks.

How do I take it?
Trexall is generally prescribed to be taken once or twice each week.... read more

Trexall comes in tablet form.

Side effects
The FDA-approved label for Trexall lists common side effects including dizziness, malaise, fatigue, chills, fever, nausea, abdominal pain, infections, mouth sores, and leukopenia (decreased white blood cells).

Rare but serious side effects listed for Trexall include toxic reactions, severe infections and blood disorders, birth defects, seizures, and damage to liver, lungs, or kidneys.

For answers to frequently asked questions about exposure to Methotrexate during pregnancy and breastfeeding, visit the experts at MothertoBaby.org.

For more details about this treatment, visit:

Trexall ā€“ RxList

Medications Used to Treat Ankylosing Spondylitis and Related Diseases ā€“ Spondylitis Association of America

Trexall (Methotrexate) Questions

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