Biologics aren't pain relievers or energy supplements. They target one particular type of protein molecule called a cytokihe that your dr THINKS you MIGHT have that is causing your pain and fatigue. IF that is the only one, it MIGHT work by blocking the activity of the molecule. If it not the right one, or if you have more than one cytokine activity, by trial and error, not only will Taltz do nothing at all, it could easily make you much much much worse, like cancer worse. Sorry to be the bearer if this is the first you've heard about that. Read the fine print with your meds. Do your resaerch due diligence to save your life. It is what it is.