I recently found out my B3 / niacin levels are on the ragged low edge of normal and have since had other practitioners point out visual signs of a niacin deficiency. I've been reading up and there is some good data on supplementing with high dose Niacin and Niacinamide for arthritis related symptoms but not a lot of clear information on safe dosages often safe dosage indications are much lower than data supporting good results and I'm finding lots of warnings for high dose usage and long term… read more
Since it is a water soluble vitamin higher doses will just be excreted through your kidneys. It would be ok to take a regular dose and see how you feel.
May help